Pantothenic Acid Content of Human Blood

Aging effect of blood pantothenic acid content in female.

In the previous reports (Ishiguro 1961, Ishiguro et al. 1961) the author has pointed out that the pantothenic acid content in blood of rural inhabitants decreases with age, particularly in females. In the following study (Ishiguro 1962), the author reported that the blood pantothenic acid contents of pregnant women showed the level lower than that of non-pregnant women at the same age groups, a...

The pantothenic acid content of coenzyme A by chick assay.

Lipmann, Kaplan, Novelli, Tuttle, and Guirard (1) reported that, whereas concentrates of the coenzyme required for acetylation (coenzyme A) showed no pantothenic acid activity by the ordinary microbiological assay, considerable amounts of p-alanine were found after acid hydrolysis. From this early observation, it was suspected that the coenzyme might contain combined pantothenic acid which was ...

Pantothenic acid deficiency induced in human subjects.

Bean and Hodges (1) gave a preliminary report of four young men in whom clinical disorders and metabolic faults were induced by a "diet" devoid of pantothenic acid, with omega-methylpantothenic acid, a vitamin antagonist (Figure 1). It is proposed here to describe details of the experiments, results, and some interpretations. The background for using molecular antagonists (2, 3) in human nutrit...

Microbic Decomposition of Pantothenic Acid.

The metabolism of pantothenic acid.

The formulation of this pathway was based on: (a) the finding that cysteine supplies the sulfur-containing moiety of CoA (3,4); (b) the activities of pantetheine and pantothenylcysteine as growth factors for Acetobacter suboxydans (4-6) and Lactobacillus helveticus (7); (c) the presence of enzymes in these two organisms and also in Lactobacillus bulgur&s which decarboxylate pantothenylcysteine ...